The arthritis severity locus Cia5a regulates the expression of inflammatory mediators including Syk pathway genes and proteases in pristane-induced arthritis
Abstract Background Cia5a is a locus on rat chromosome 10 that regulates disease severity and joint damage in two models of rheumatoid arthritis, collagen- and pristane-induced arthritis (PIA).In this study, we aimed to identify cellular and molecular processes regulated by Cia5a using microarray-based gene expression Extractors analysis of synovia